What this trial means for you
This study is active, not recruiting — it is not currently taking new participants, but its results may matter for treatments you're considering. It's studying Mazdutide, Placebo for alcohol use disorder.
What participants typically get: study medication (or placebo, if the trial uses one) and study-related medical care at no cost, plus close monitoring. Compensation for time and travel varies by study — ask the site. Note that in many trials you can't choose your treatment group, and some participants receive a placebo.
The study, in the sponsor's words
The objective of this proof-of-concept study to evaluate mazdutide in participants with alcohol use disorder (AUD). For any individual participant, the maximum duration of study participation is approximately 36 weeks, including screening and posttreatment follow-up.
Can you join? The exact criteria
Below is the verbatim eligibility text from the registry — bring it to your doctor; it's written for clinicians, and your own clinician is the right person to interpret it with you.
Full eligibility criteria (for you and your doctor)
Inclusion Criteria: * Current AUD diagnosis as defined by Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 criteria. Exclusion Criteria: * Have a history of significant active or unstable major depressive disorder, suicidal ideation, or other severe psychiatric disorder within the last 12 months. * Have initiated psychotherapy, changed the intensity of psychotherapy, or other nondrug therapies (for example, acupuncture or hypnosis) within 8 weeks prior to enrollment. * Have received any medication for AUD in the last 30 days including but not limited to, disulfiram, acamprosate, naltrexone, gabapentin, baclofen, or topiramate. * Other protocol-specific inclusion and exclusion criteria may apply.
Study sites by state
Arizona
- Headlands Research - Scottsdale — Scottsdale
Arkansas
- Woodland Resarch Northwest/ERG — Rogers
California
- Ark Clinical Research - Fountain Valley — Fountain Valley
- Synergy San Diego — Lemon Grove
- Headlands Research-Artemis San Diego — San Diego
Florida
- Research Centers of America ( Hollywood ) — Hollywood
- K2 Medical Research - Maitland — Maitland
- K2 Medical Research — Maitland
- Clinical Neuroscience Solutions Inc — Orlando
- Clinical Neuroscience Solutions, Inc. — Orlando
- K2 Medical Research - Tampa — Tampa
Georgia
- CenExel iResearch, LLC (CenExel iRA) — Decatur
Louisiana
- DelRicht Research — Mandeville
Massachusetts
- Adams Clinical — Watertown
- Vitalix Clinical — Worcester
Nevada
- Redbird Research LLC — Las Vegas
New York
- Richmond Behavioral Associates — Staten Island
- Ichor Research — Syracuse
- Davis Clinical — The Bronx
Oregon
- Summit Headlands — Portland
Rhode Island
- Rhode Island Mood & Memory Research Institute — East Providence
South Carolina
- Medical University of South Carolina — Charleston
Tennessee
- Clinical Neuroscience Solutions Inc — Memphis
Texas
- FutureSearch Trials of Dallas — Dallas
- Dallas Clinical Research Center/Pillar Research — Richardson
View the official record on ClinicalTrials.gov →
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