When your cells stop responding well to insulin, so your body makes more of it to keep blood sugar in check — a core driver of prediabetes and type 2 diabetes. It's closely tied to weight and the broader cardiometabolic picture. GLP-1 medications can improve blood sugar control, which is part of why they're used in diabetes as well as weight management.
Related terms: Type 2 diabetes · Prediabetes · A1c (HbA1c) · Cardiometabolic