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HomeTrials › NCT05872022

Obesity & weight · Not applicable · By invitation only

A Study to Evaluate Safety of Exposure to Wegovy During Pregnancy

NCT05872022 · Sponsor: Novo Nordisk A/S

What this trial means for you

This study is by invitation only — it is not currently taking new participants, but its results may matter for treatments you're considering. It's studying see the official record for pregnancy, obesity, overweight.

Who can joinWomen, 15 Years – 50 Years
Healthy volunteersNo — diagnosis required
What you'd takesee the official record
Study length~9.3 years overall
Planned participants728
TypeObservational (no assigned treatment)

What participants typically get: study medication (or placebo, if the trial uses one) and study-related medical care at no cost, plus close monitoring. Compensation for time and travel varies by study — ask the site. Note that in many trials you can't choose your treatment group, and some participants receive a placebo.

The study, in the sponsor's words

This is an observational, prospective Wegovy (semaglutide 2.4 milligram \[mg\]) Pregnancy Registry Study. The aim of this study is to compare the maternal, foetal, and infant outcomes of pregnant women who are exposed to Wegovy during pregnancy for the treatment of obesity or overweight with at least one weight-related comorbid condition with outcomes in an internal comparison cohort of pregnant women with obesity or overweight with at least one weight related comorbid condition at conception and who are not exposed to Wegovy or other glucagon-like peptide-1 receptor agonists (GLP-1 RAs) during pregnancy. Infant outcomes will be assessed throughout the infant's first year of life, with active data collection by the registry occurring at 4 and 12 months after delivery.

Can you join? The exact criteria

Below is the verbatim eligibility text from the registry — bring it to your doctor; it's written for clinicians, and your own clinician is the right person to interpret it with you.

Full eligibility criteria (for you and your doctor)

Inclusion Criteria: * Signed consent obtained before any study-related activities * Female 15-50 years of age at the time of signing consent * Currently or recently pregnant * Resident of country included in the study * Authorisation for her HCP(s) to provide data to the registry * Exposed to Wegovy cohort: Exposure to at least one dose of Wegovy at any time during pregnancy for the treatment of obesity or overweight with at least one weight-related comorbid condition. * Unexposed to Wegovy cohort: Have obesity or overweight with at least one weight related comorbid condition at conception Exclusion Criteria: * Mental incapacity, unwillingness, or language barriers precluding adequate understanding or cooperation * Unexposed to Wegovy cohort: Exposure to Wegovy or other GLP-1 RA at any time during pregnancy

Study sites by state

New Jersey

  • Novo Nordisk Investigational Site — Princeton

View the official record on ClinicalTrials.gov →

Verify before you act. Medical disclaimer: content on this site is for informational purposes only and is not medical advice. GLP-1 medications are prescription drugs; always consult a licensed healthcare provider about eligibility, risks, and benefits. Trial details and enrollment status change frequently — always verify on the official registry and talk to your own clinician before contacting a study site. This page was generated from registry data and is not affiliated with the study sponsor.

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