What this trial means for you
This study is active, not recruiting — it is not currently taking new participants, but its results may matter for treatments you're considering. It's studying Orforglipron, Placebo for hypertension, overweight or obesity.
What participants typically get: study medication (or placebo, if the trial uses one) and study-related medical care at no cost, plus close monitoring. Compensation for time and travel varies by study — ask the site. Note that in many trials you can't choose your treatment group, and some participants receive a placebo.
The study, in the sponsor's words
GZL1 is an independent study conducted under the GZPL master protocol. GZL1 will evaluate the efficacy and safety of orforglipron for treatment of hypertension in participants with obesity or overweight.
Can you join? The exact criteria
Below is the verbatim eligibility text from the registry — bring it to your doctor; it's written for clinicians, and your own clinician is the right person to interpret it with you.
Full eligibility criteria (for you and your doctor)
Inclusion Criteria: * refer to the GZPL master protocol for screening eligibility. Exclusion Criteria: * refer to the GZPL master protocol for screening eligibility.
Study sites by state
Arizona
- Elite Clinical Studies, LLC — Phoenix
California
- Valley Clinical Trials, Inc. — Covina
- Valley Clinical Trials, Inc. — Northridge
Connecticut
- Chase Medical Research, LLC — Waterbury
Florida
- Excel Medical Clinical Trials — Boca Raton
- Care Access - Brandon — Brandon
- Northeast Research Institute - Downtown Office — Jacksonville
- Peace River Cardiovascular Center — Port Charlotte
Hawaii
- East-West Medical Research Institute — Honolulu
Maryland
- Ascension Saint Agnes Heart Care — Baltimore
Massachusetts
- Lucida Clinical Trials — New Bedford
Michigan
- Arcturus Healthcare , PLC, Troy Internal Medicine Research Division — Troy
Missouri
- StudyMetrix Research — City of Saint Peters
Nevada
- Excel Clinical Research, LLC — Las Vegas
- Palm Research Center Sunset — Las Vegas
New York
- Rochester Clinical Research, LLC — Rochester
Ohio
- Remington-Davis, Inc — Columbus
- PriMED Clinical Research — Dayton
Oregon
- Advanced Research Institute - Tigard — Tigard
South Carolina
- Care Access - Mauldin — Mauldin
Texas
- Dallas Heart and Vascular Consultants, PA — Duncanville
- Texas Institute of Cardiology, PA — McKinney
- North Hills Family Medicine/North Hills Medical Research — North Richland Hills
Utah
- Advanced Research Institute — Ogden
Virginia
- Carient Heart & Vascular - Manassas — Manassas
- Health Research of Hampton Roads, Inc. — Newport News
- National Clinical Research, Inc — Richmond
Washington
- Eastside Research Associates — Redmond
View the official record on ClinicalTrials.gov →
Follow this trial
Get an email when our monthly digest covers enrollment changes and results for trials like this one.
Newsletter signup launches soon. (Site owner: set PUBLIC_BUTTONDOWN_USERNAME in
.env to activate this form.)