What this trial means for you
This study is recruiting now at 25 US sites. It's studying Retatrutide, Placebo for obesity, overweight, chronic low back pain (clbp).
What participants typically get: study medication (or placebo, if the trial uses one) and study-related medical care at no cost, plus close monitoring. Compensation for time and travel varies by study — ask the site. Note that in many trials you can't choose your treatment group, and some participants receive a placebo.
The study, in the sponsor's words
The main purpose of this study is to evaluate the efficacy and safety of retatrutide in relieving chronic low back pain in participants who have obesity or overweight. Participation in the study will last about 80 weeks.
Can you join? The exact criteria
Below is the verbatim eligibility text from the registry — bring it to your doctor; it's written for clinicians, and your own clinician is the right person to interpret it with you.
Full eligibility criteria (for you and your doctor)
Inclusion Criteria: * Have a history of axial-predominant low back pain * Have pain that is restricted to the low back or with a referral pattern limited to the proximal legs * Have a body mass index (BMI) ≥27 kilograms per square meter (kg/m2) at screening * Have a history of at least 1 self-reported unsuccessful dietary effort to lose body weight Exclusion Criteria: * Have a non-axial origin low back pain * Have had botulinum or steroid injections to the spine within 1 year of screening * Have had trigger point injection to the spine within 6 months of screening * Have a self-reported change in body weight \>5 kilograms (kg) (11 pounds) within 90 days prior to screening * Have been taking drugs to promote body weight reduction, including over-the-counter medications, within 90 days prior to screening * Have a prior or planned surgical treatment for obesity * Have Type 1 Diabetes, Type 2 Diabetes, or any other type of diabetes
Study sites by state
Arizona
- MD First Research - Chandler — Chandler · Recruiting now
- Tucson Orthopaedic Institute - North Wyatt Drive — Tucson · Recruiting now
California
- Ark Clinical Research - Fountain Valley — Fountain Valley · Recruiting now
- St Joseph Heritage Healthcare — Fullerton · Recruiting now
- Clinical Research Institute — Los Angeles · Recruiting now
- Artemis Institute for Clinical Research — San Diego · Recruiting now
Colorado
- Alpine Clinical Research Center — Boulder · Recruiting now
Florida
- K2 Medical Research - Daytona Beach — Daytona Beach · Recruiting now
- Flourish Research - Miami, LLC — Miami · Recruiting now
- IMA Clinical Research St. Petersburg — St. Petersburg · Recruiting now
- Care Access - Tampa — Tampa · Recruiting now
- Charter Research - Lady Lake — The Villages · Recruiting now
- Conquest Research — Winter Park · Recruiting now
Kansas
- Cotton O'Neil Clinical Research Center — Topeka · Recruiting now
Louisiana
- Care Access - Lake Charles (Bayou Pines) — Lake Charles · Recruiting now
Massachusetts
- MedVadis Research Corporation — Waltham · Recruiting now
Michigan
- Great Lakes Research Group, Inc. — Bay City · Recruiting now
Missouri
- Clinvest Headlands Llc — Springfield · Recruiting now
North Carolina
- Center for Clinical Research — Winston-Salem · Recruiting now
Pennsylvania
- Altoona Center For Clinical Research — Duncansville · Recruiting now
Tennessee
- New Phase Research and Development — Knoxville · Recruiting now
Texas
- FutureSearch Trials of Neurology — Austin · Recruiting now
- Mercy Family Clinic — Dallas · Recruiting now
- Houston Research Institute — Houston · Recruiting now
Virginia
- Sovah Clinical Research-River District — Danville · Recruiting now
View the official record on ClinicalTrials.gov →
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