What this trial means for you
This study is recruiting now at 10 US sites. It's studying Tradipitant, Placebo for nausea and vomiting, obesity.
What participants typically get: study medication (or placebo, if the trial uses one) and study-related medical care at no cost, plus close monitoring. Compensation for time and travel varies by study, ask the site. Note that in many trials you can't choose your treatment group, and some participants receive a placebo.
The study, in the sponsor's words
The goal of this study is to measure the effects of using Tradipitant to treat nausea and vomiting induced by GLP-1R agonist use in adults with class I or class II obesity, or adults who are overweight with at least one weight-related condition. The study is placebo-controlled with two treatment arms.
Can you join? The exact criteria
Below is the verbatim eligibility text from the registry. Bring it to your doctor; it's written for clinicians, and your own clinician is the right person to interpret it with you.
Full eligibility criteria (for you and your doctor)
Inclusion Criteria: * Body Mass Index ≥ 25 and \< 40 kg/m\^2 * No serious medical problems or chronic diseases, specifically no type I or type II diabetes Exclusion Criteria: * Another disorder that contributes to gastrointestinal symptoms * History of intolerance and/or hypersensitivity to NK-1 receptor antagonists * History of intolerance and/or hypersensitivity to GLP-1 receptor agonists * Exposure to any investigational medication within the past 60 days
Study sites by state
California
- Vanda Investigational Site, Los Angeles · Recruiting now
- Vanda Investigational Site, San Diego · Recruiting now
- Vanda Investigational Site, San Jose · Opening soon
Florida
- Vanda Investigational Site, Tampa · Recruiting now
New Jersey
- Vanda Investigational Site, Hamilton · Opening soon
New York
- Vanda Investigational Site, New York · Opening soon
- Vanda Investigational Site, Syosset · Opening soon
Texas
- Vanda Investigational Site, Plano · Opening soon
- Vanda Investigational Site, San Antonio · Opening soon
Virginia
- Vanda Investigational Site, Burke · Opening soon
View the official record on ClinicalTrials.gov →
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