What this trial means for you
This study is recruiting now at 10 US sites. It's studying Tradipitant, Placebo for nausea and vomiting, obesity.
What participants typically get: study medication (or placebo, if the trial uses one) and study-related medical care at no cost, plus close monitoring. Compensation for time and travel varies by study — ask the site. Note that in many trials you can't choose your treatment group, and some participants receive a placebo.
The study, in the sponsor's words
The goal of this study is to measure the effects of using Tradipitant to treat nausea and vomiting induced by GLP-1R agonist use in adults with class I or class II obesity, or adults who are overweight with at least one weight-related condition. The study is placebo-controlled with two treatment arms.
Can you join? The exact criteria
Below is the verbatim eligibility text from the registry — bring it to your doctor; it's written for clinicians, and your own clinician is the right person to interpret it with you.
Full eligibility criteria (for you and your doctor)
Inclusion Criteria: * Body Mass Index ≥ 25 and \< 40 kg/m\^2 * No serious medical problems or chronic diseases, specifically no type I or type II diabetes Exclusion Criteria: * Another disorder that contributes to gastrointestinal symptoms * History of intolerance and/or hypersensitivity to NK-1 receptor antagonists * History of intolerance and/or hypersensitivity to GLP-1 receptor agonists * Exposure to any investigational medication within the past 60 days
Study sites by state
California
- Vanda Investigational Site — Los Angeles · Recruiting now
- Vanda Investigational Site — San Diego · Recruiting now
- Vanda Investigational Site — San Jose · Opening soon
Florida
- Vanda Investigational Site — Tampa · Recruiting now
New Jersey
- Vanda Investigational Site — Hamilton · Opening soon
New York
- Vanda Investigational Site — New York · Opening soon
- Vanda Investigational Site — Syosset · Opening soon
Texas
- Vanda Investigational Site — Plano · Opening soon
- Vanda Investigational Site — San Antonio · Opening soon
Virginia
- Vanda Investigational Site — Burke · Opening soon
View the official record on ClinicalTrials.gov →
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