What this trial means for you
This study is recruiting now at 99 US sites. It's studying Cagrisema, Semaglutide for obesity, type 2 diabetes.
What participants typically get: study medication (or placebo, if the trial uses one) and study-related medical care at no cost, plus close monitoring. Compensation for time and travel varies by study, ask the site. Note that in many trials you can't choose your treatment group, and some participants receive a placebo.
The study, in the sponsor's words
This clinical study is testing how the study medicine CagriSema helps people living with obesity, with or without type 2 diabetes (T2D), lose weight. The purpose of the study is to find out how safe and effective CagriSema is for body weight loss in these participants. Participants will receive either CagriSema or semaglutide, and which treatment participants receive is decided by chance. CagriSema is a new study medicine being tested, while semaglutide is a medicine that doctors can already prescribe. The study will last for about 83 weeks
Can you join? The exact criteria
Below is the verbatim eligibility text from the registry. Bring it to your doctor; it's written for clinicians, and your own clinician is the right person to interpret it with you.
Full eligibility criteria (for you and your doctor)
Inclusion Criteria : * Male or female (sex assigned at birth, inclusive of all gender identities). * Age 18 years or above at the time of signing the informed consent. * BMI≥ 35.0 kg/m\^2. * Participants without T2D: No history of T2D and HbA1c \< 6.5% (48 millimoles per mole (mmol/mol)) Participants with T2D: A history of T2D and HbA1c \< 10% (\< 86 mmol/mol). If a participant without a history of diabetes during the screening period receives an HbA1c result of 6.5% (48 mmol/mol) or higher, the investigator or the participant's healthcare provider must confirm the diagnosis of type 2 diabetes before the participant is randomised. Exclusion Criteria: * A self-reported change in body weight \> 5% within 90 days before screening, irrespective of medical records. * Use of any glucagon-like-peptide-1 receptor agonist (GLP-1 RA), including medication with GLP-1 RA activity, or amylin analogues, including medication with amylin activity, within 6 months before screening.
Study sites by state
Alabama
- Uni of Alabama at Birmingham, Birmingham · Active, not recruiting
- Cahaba Research, Pelham · Active, not recruiting
Arizona
- Elligo Health Research Inc, Gilbert · Active, not recruiting
- Velocity Clinical Research-Phoenix, Phoenix · Active, not recruiting
Arkansas
- Arkansas Clinical Research, Little Rock · Active, not recruiting
- Woodland Int. Research Group, Little Rock · Active, not recruiting
California
- Headlands Research California, LLC, Escondido · Active, not recruiting
- Neighborhood Healthcare, Escondido · Active, not recruiting
- Diabetes & Endocrine Specialists - La Mesa, La Mesa · Active, not recruiting
- Clinical Trials Research_Sacramento, Lincoln · Active, not recruiting
- Loma Linda University Faculty Medical Clinics, Loma Linda · Active, not recruiting
- Pacific Clinical Studies, Los Alamitos · Active, not recruiting
- Valley Clinical Trials, Northridge · Active, not recruiting
- Desert Oasis Healthcare, Palm Springs · Active, not recruiting
- Linda Vista Health Care Ctr, San Diego · Active, not recruiting
- Velocity Clin Res - Van Nuys, Van Nuys · Active, not recruiting
- Flourish Research - CA, Walnut Creek · Active, not recruiting
Colorado
- University of Colorado Hospital, Aurora · completed
Florida
- TBMR & Alcanza, Clearwater · Active, not recruiting
- Northeast Research Institute, Fleming Island · Active, not recruiting
- Northeast Research Institute, Jacksonville · Active, not recruiting
- Westside Center For Clinical Research, Jacksonville · Active, not recruiting
- Bioclinical Research Alliance, Miami · Active, not recruiting
- New Horizon Research Center, Miami · Active, not recruiting
- South Broward Research LLC, Miramar · Active, not recruiting
- West Orange Endocrinology, Ocoee · Active, not recruiting
- Oviedo Medical Research, LLC, Oviedo · Active, not recruiting
- Clinical Trial Services Corp, Pembroke Pines · Active, not recruiting
Georgia
- Hope Clin Res & Wellness, Conyers · Active, not recruiting
- Center for Adv Res & Education, Gainesville · Active, not recruiting
- Endocrine Research Solutions, Inc, Roswell · Active, not recruiting
- North Georgia Clinical Research, Woodstock · Active, not recruiting
Idaho
- Solaris Clinical Research, Meridian · Active, not recruiting
Illinois
- Cedar-Crosse Research Center, Chicago · Active, not recruiting
- Macoupin Fam Practice Ctr, LLP, Gillespie · Active, not recruiting
- Clinical Investigation Spec Gurnee, Gurnee · Active, not recruiting
- Endeavor Health, Skokie · Active, not recruiting
- Evanston Premier Hlthcr Res, Skokie · Active, not recruiting
Iowa
- Iowa Diabetes Research, West Des Moines · Active, not recruiting
Kansas
- Alliance for Multispecialty Research, Newton · Active, not recruiting
- Cotton O'Neil Diab & Endo Ctr, Topeka · Active, not recruiting
Kentucky
- The Research Group of Lexington LLC, Lexington · Active, not recruiting
Maryland
- Endo and Metabolic Consultants, Rockville · Opening soon
Michigan
- Northern Pines Hlth Ctr, PC, Buckley · Active, not recruiting
Minnesota
- International Diabetes Center, Minneapolis · Opening soon
- AES Minneapolis DRS, Richfield · Active, not recruiting
Mississippi
- Belzoni Clinical Research, Belzoni · Active, not recruiting
Missouri
- Clinical Research Professionals, Chesterfield · Active, not recruiting
- Amicis Centers of Clinical Research, St Louis · Active, not recruiting
New York
- Southgate Medical Group, LLP, West Seneca · Active, not recruiting
North Carolina
- PharmQuest Life Sciences LLC, Greensboro · Active, not recruiting
- Physician's East Endocrinology, Greenville · Active, not recruiting
- Carteret Medical Group, Morehead City · Active, not recruiting
- Centricity Rsrch MHCity Multi, Morehead City · Active, not recruiting
- Piedmont Healthcare/Research, Statesville · Active, not recruiting
- Accellacare Wilmington, Wilmington · Active, not recruiting
North Dakota
- Lillestol Research LLC, Fargo · Active, not recruiting
- Plains Clinical Research Center, LLC, Fargo · Opening soon
Ohio
- Advanced Medical Research, Maumee · Active, not recruiting
Oklahoma
- Alliance for Multispecialty Research, Norman · Active, not recruiting
- Lynn Institute of Norman, Norman · Active, not recruiting
Pennsylvania
- Heritage Valley Medical Group, Beaver · Opening soon
- Hatboro Med Associates, Hatboro · Active, not recruiting
- Northeast Endocrine Metabolic Associates, Philadelphia · Active, not recruiting
Rhode Island
- Clinical Res Collaborative, Cumberland · Active, not recruiting
South Carolina
- Velocity Clinical Research-Gaffney, Gaffney · Active, not recruiting
- Spartanburg Medical Research, Spartanburg · Active, not recruiting
Tennessee
- Jackson Clinic, Jackson · Active, not recruiting
- Holston Medical Group, Kingsport · Active, not recruiting
- CNS Healthcare, Memphis · Active, not recruiting
- HealthStar Physicians, PC, Morristown · Active, not recruiting
- Clinical Research Associates, Nashville · Active, not recruiting
Texas
- Amarillo Med Spec LLP, Amarillo · Active, not recruiting
- Texas Diab & Endo, P.A., Austin · Active, not recruiting
- Velocity Clinical Research Austin, Austin · Active, not recruiting
- Velocity Clin Res, Dallas, Dallas · Active, not recruiting
- North Texas Endocrine Center, Dallas · Active, not recruiting
- Cedar Health Research, Euless · Active, not recruiting
- JCCT- Juno NW Houston, Houston · Active, not recruiting
- The Endocrine Center, Houston · Active, not recruiting
- Medical Colleagues-Texas LLP, Katy · Active, not recruiting
- Sante Clinical Research, Kerrville · Active, not recruiting
- Radiance Clinical Research, Lampasas · Active, not recruiting
- Aeres Clinical Research, Laredo · Active, not recruiting
- DCOL Ctr for Clin Res, Longview · Active, not recruiting
- RGV Endocrine Center, McAllen · Active, not recruiting
- Quality Research Inc, San Antonio · Active, not recruiting
- AES San Antonio, San Antonio · Active, not recruiting
- Northeast Clinical Research of San Antonio, San Antonio · Active, not recruiting
- Consano Clinical Research, LLC, Shavano Park · Active, not recruiting
- Mt Olympus Medical Research, LLC, Sugar Land · Active, not recruiting
Utah
- J.Lewis Research Inc, Salt Lake City · Active, not recruiting
- J.Lewis Research Inc, Salt Lake City · Active, not recruiting
- Diabetes & Endo Tx Specialists, Sandy City · Active, not recruiting
- J.Lewis Research Inc, South Jordan · Active, not recruiting
Virginia
- Health Res of Hampton Roads, Newport News · Active, not recruiting
- Tidewater Physicians Multispecialty Group, Newport News · Active, not recruiting
- National Clin Res Inc., Richmond · Active, not recruiting
Wisconsin
- Prevea Health, Green Bay · Opening soon
View the official record on ClinicalTrials.gov →
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