What this trial means for you
This study is recruiting now at 99 US sites. It's studying Cagrisema, Semaglutide for obesity, type 2 diabetes.
What participants typically get: study medication (or placebo, if the trial uses one) and study-related medical care at no cost, plus close monitoring. Compensation for time and travel varies by study — ask the site. Note that in many trials you can't choose your treatment group, and some participants receive a placebo.
The study, in the sponsor's words
This clinical study is testing how the study medicine CagriSema helps people living with obesity, with or without type 2 diabetes (T2D), lose weight. The purpose of the study is to find out how safe and effective CagriSema is for body weight loss in these participants. Participants will receive either CagriSema or semaglutide, and which treatment participants receive is decided by chance. CagriSema is a new study medicine being tested, while semaglutide is a medicine that doctors can already prescribe. The study will last for about 83 weeks
Can you join? The exact criteria
Below is the verbatim eligibility text from the registry — bring it to your doctor; it's written for clinicians, and your own clinician is the right person to interpret it with you.
Full eligibility criteria (for you and your doctor)
Inclusion Criteria : * Male or female (sex assigned at birth, inclusive of all gender identities). * Age 18 years or above at the time of signing the informed consent. * BMI≥ 35.0 kg/m\^2. * Participants without T2D: No history of T2D and HbA1c \< 6.5% (48 millimoles per mole (mmol/mol)) Participants with T2D: A history of T2D and HbA1c \< 10% (\< 86 mmol/mol). If a participant without a history of diabetes during the screening period receives an HbA1c result of 6.5% (48 mmol/mol) or higher, the investigator or the participant's healthcare provider must confirm the diagnosis of type 2 diabetes before the participant is randomised. Exclusion Criteria: * A self-reported change in body weight \> 5% within 90 days before screening, irrespective of medical records. * Use of any glucagon-like-peptide-1 receptor agonist (GLP-1 RA), including medication with GLP-1 RA activity, or amylin analogues, including medication with amylin activity, within 6 months before screening.
Study sites by state
Alabama
- Uni of Alabama at Birmingham — Birmingham · Opening soon
- Cahaba Research — Pelham · Recruiting now
Arizona
- Elligo Health Research Inc — Gilbert · Opening soon
- Velocity Clinical Research-Phoenix — Phoenix · Recruiting now
Arkansas
- Arkansas Clinical Research — Little Rock · Recruiting now
- Woodland Int. Research Group — Little Rock · Opening soon
California
- Headlands Research California, LLC — Escondido · Recruiting now
- Neighborhood Healthcare — Escondido · Recruiting now
- Diabetes & Endocrine Specialists - La Mesa — La Mesa · Recruiting now
- Clinical Trials Research_Sacramento — Lincoln · Recruiting now
- Loma Linda University Faculty Medical Clinics — Loma Linda · Opening soon
- Pacific Clinical Studies — Los Alamitos · Recruiting now
- Valley Clinical Trials — Northridge · Recruiting now
- Desert Oasis Healthcare — Palm Springs · Recruiting now
- Linda Vista Health Care Ctr — San Diego · Recruiting now
- Velocity Clin Res - Van Nuys — Van Nuys · Recruiting now
- Flourish Research - CA — Walnut Creek · Recruiting now
Colorado
- University of Colorado Hospital — Aurora · Opening soon
Florida
- TBMR & Alcanza — Clearwater · Recruiting now
- Northeast Research Institute — Fleming Island · Recruiting now
- Northeast Research Institute — Jacksonville · Recruiting now
- Westside Center For Clinical Research — Jacksonville · Opening soon
- Bioclinical Research Alliance — Miami · Recruiting now
- New Horizon Research Center — Miami · Recruiting now
- South Broward Research LLC — Miramar · Recruiting now
- West Orange Endocrinology — Ocoee · Recruiting now
- Oviedo Medical Research, LLC — Oviedo · Recruiting now
- Clinical Trial Services Corp — Pembroke Pines · Opening soon
Georgia
- Hope Clin Res & Wellness — Conyers · Recruiting now
- Center for Adv Res & Education — Gainesville · Recruiting now
- Endocrine Research Solutions, Inc — Roswell · Recruiting now
- North Georgia Clinical Research — Woodstock · Recruiting now
Idaho
- Solaris Clinical Research — Meridian · Recruiting now
Illinois
- Cedar-Crosse Research Center — Chicago · Opening soon
- Macoupin Fam Practice Ctr, LLP — Gillespie · Recruiting now
- Clinical Investigation Spec Gurnee — Gurnee · Recruiting now
- Endeavor Health — Skokie · Opening soon
- Evanston Premier Hlthcr Res — Skokie · Recruiting now
Iowa
- Iowa Diabetes Research — West Des Moines · Opening soon
Kansas
- Alliance for Multispecialty Research — Newton · Recruiting now
- Cotton O'Neil Diab & Endo Ctr — Topeka · Recruiting now
Kentucky
- The Research Group of Lexington LLC — Lexington · Recruiting now
Maryland
- Endo and Metabolic Consultants — Rockville · Opening soon
Michigan
- Northern Pines Hlth Ctr, PC — Buckley · Recruiting now
Minnesota
- International Diabetes Center — Minneapolis · Opening soon
- AES Minneapolis DRS — Richfield · Recruiting now
Mississippi
- Belzoni Clinical Research — Belzoni · Opening soon
Missouri
- Clinical Research Professionals — Chesterfield · Recruiting now
- Amicis Centers of Clinical Research — St Louis · Recruiting now
New York
- Southgate Medical Group, LLP — West Seneca · Recruiting now
North Carolina
- PharmQuest Life Sciences LLC — Greensboro · Recruiting now
- Physician's East Endocrinology — Greenville · Recruiting now
- Carteret Medical Group — Morehead City · Recruiting now
- Centricity Rsrch MHCity Multi — Morehead City · Recruiting now
- Piedmont Healthcare/Research — Statesville · Recruiting now
- Accellacare Wilmington — Wilmington · Recruiting now
North Dakota
- Lillestol Research LLC — Fargo · Recruiting now
- Plains Clinical Research Center, LLC — Fargo · Opening soon
Ohio
- Advanced Medical Research — Maumee · Recruiting now
Oklahoma
- Alliance for Multispecialty Research — Norman · Recruiting now
- Lynn Institute of Norman — Norman · Recruiting now
Pennsylvania
- Heritage Valley Medical Group — Beaver · Opening soon
- Hatboro Med Associates — Hatboro · Recruiting now
- Northeast Endocrine Metabolic Associates — Philadelphia · Opening soon
Rhode Island
- Clinical Res Collaborative — Cumberland · Recruiting now
South Carolina
- Velocity Clinical Research-Gaffney — Gaffney · Opening soon
- Spartanburg Medical Research — Spartanburg · Recruiting now
Tennessee
- Jackson Clinic — Jackson · Recruiting now
- Holston Medical Group — Kingsport · Recruiting now
- CNS Healthcare — Memphis · Recruiting now
- HealthStar Physicians, PC — Morristown · Recruiting now
- Clinical Research Associates — Nashville · Recruiting now
Texas
- Amarillo Med Spec LLP — Amarillo · Recruiting now
- Texas Diab & Endo, P.A. — Austin · Recruiting now
- Velocity Clinical Research Austin — Austin · Recruiting now
- Velocity Clin Res, Dallas — Dallas · Recruiting now
- North Texas Endocrine Center — Dallas · Recruiting now
- Cedar Health Research — Euless · Opening soon
- JCCT- Juno NW Houston — Houston · Recruiting now
- The Endocrine Center — Houston · Recruiting now
- Medical Colleagues-Texas LLP — Katy · Opening soon
- Sante Clinical Research — Kerrville · Recruiting now
- Radiance Clinical Research — Lampasas · Recruiting now
- Aeres Clinical Research — Laredo · Recruiting now
- DCOL Ctr for Clin Res — Longview · Recruiting now
- RGV Endocrine Center — McAllen · Recruiting now
- Quality Research Inc — San Antonio · Recruiting now
- AES San Antonio — San Antonio · Recruiting now
- Northeast Clinical Research of San Antonio — San Antonio · Recruiting now
- Consano Clinical Research, LLC — Shavano Park · Recruiting now
- Mt Olympus Medical Research, LLC — Sugar Land · Recruiting now
Utah
- J.Lewis Research Inc — Salt Lake City · Recruiting now
- J.Lewis Research Inc — Salt Lake City · Recruiting now
- Diabetes & Endo Tx Specialists — Sandy City · Opening soon
- J.Lewis Research Inc — South Jordan · Recruiting now
Virginia
- Health Res of Hampton Roads — Newport News · Recruiting now
- Tidewater Physicians Multispecialty Group — Newport News · Recruiting now
- National Clin Res Inc. — Richmond · Recruiting now
Wisconsin
- Prevea Health — Green Bay · Opening soon
View the official record on ClinicalTrials.gov →
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