What this trial means for you
This study is opening soon at 1 US site. It's studying see the official record for women's health, obesity & overweight, perimenopausal women.
What participants typically get: study medication (or placebo, if the trial uses one) and study-related medical care at no cost, plus close monitoring. Compensation for time and travel varies by study, ask the site. Note that in many trials you can't choose your treatment group, and some participants receive a placebo.
The study, in the sponsor's words
The goal of PLAN-RT 1.0 to learn if a 12-week app-based strength training program can help midlife women build and stick with a regular strength training routine while they are taking GLP-1 medication for weight loss. PLAN-RT 1.0 targets women ages 40 to 59 who were not regularly exercising before starting GLP-1 medication. The main questions this study aims to answer are: (1) Is the PLAN-RT 1.0 program feasible and acceptable to participants (based on how many people join, stay in the study, and use the program)? (2) Does the program lead to early changes in muscle strength, body composition, physical function, and exercise habits?
Can you join? The exact criteria
Below is the verbatim eligibility text from the registry. Bring it to your doctor; it's written for clinicians, and your own clinician is the right person to interpret it with you.
Full eligibility criteria (for you and your doctor)
Inclusion Criteria: Participants must meet all of the following criteria: * Female, age 40 to 54 years. * Recently initiated GLP-1 receptor agonist (GLP-1RA) therapy within the past 6 months. * Body mass index (BMI) ≥27 kg/m². * Not currently participating in regular resistance training (self-reported absence of regular resistance training during the previous month). * Able to stand, sit, and perform bodyweight movements without assistive devices. * Owns a compatible smartphone (iOS or Android) with cellular or Wi-Fi access and is willing to use study applications. * Able to read, understand, and provide informed consent in English. * Willing and able to attend required in-person study visits. Exclusion Criteria: Participants will be excluded if they meet any of the following criteria: * Plans to discontinue GLP-1RA therapy or substantially modify treatment during the 12-week study period. * Self-reported musculoskeletal injury, orthopedic limitation, or surgery within the previous 6 months that would contraindicate resistance training participation. * Self-reported unstable cardiovascular disease or cardiac event within the previous 6 months. * Currently pregnant or planning to become pregnant during the study period. * Active eating disorder or psychiatric condition that may interfere with study participation. * Unable to use smartphone applications required for the intervention. * Current participation in another pharmacological, behavioral, weight management, or chronic disease management program that could confound study outcomes.
Study sites by state
Louisiana
- Louisiana State University School of Kinesiology, Baton Rouge
View the official record on ClinicalTrials.gov →
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